The System State feature of Windows can be backed up using DPX.
Active Directory (domain controllers only)
Boot files
COM+ class registration database
Registry
System volume (SYSVOL) (domain controllers only)
Certificate server (Certificate Authority only)
System protected files
Performance counter configuration
IIS metabase
Cluster Quorum
The Backup window displays System State and all its components. You can select System State for backup as if it were an ordinary disk. You cannot select individual components. System State components are always backed up collectively, never individually.
Consider backing up the entire node, which includes the BMR object. You can use BMR to recover the entire node, including System State and its components.
For information about backing up and restoring Active Directory, see Microsoft article http://msdn.microsoft.com/en-us/library/windows/desktop/aa384675(v=vs.85).aspx
For DPX, User Profile is not a component of the Registry within System State. User Profile is part of the System Table. As such, it can be individually backed up and restored. For more information, see Backing up System Table.
See also. For information about restoring System State, see Restoring System State in the DPX 4.9.x Reference Guide.